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Dynamic modulation of the blood–brain barrier in the healthy brain | Nature Reviews Neuroscience
Here, stimuli in the surrounding micro-environment induce macrophages to adopt pro-inflammatory or anti-inflammatory phenotypes and functions, thereby mediating inflammatory/autoimmune or homeostatic/reparative responses, respectively ( Macrophages are among the first cells to traffic to the pancreas under both physiological and diabetogenic conditions
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In comparison, only 1 of 20 antibiotic-responsive patients (5%) had borderline positive responses to ECM proteins ( P = 0.0008)
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