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Lifelong intramuscular vitamin B12 replacement is recommended for patients with deficiency caused by autoimmune gastritis, pernicious anaemia, total gastrectomy or terminal ileum resection (Table 4),19 because these conditions irreversibly impair gastrointestinal absorption, making oral B12 unreliable or ineffective even at high doses

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In these terms, the effect on the heart (cardioprotection) might be an additional part of the cytoprotective activity (for review, see, i.e., [10,11,12,13,14,15,16,17,121,122,123]), and, in particular, it might be commonly taken as proof and consequence of its innate cytoprotective activity (for review, see, i.e., [2,3,4,5,6,7,8])

keep the lid clean and the cap on when not in use