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To isolate the effects of lactation on alcohol pharmacokinetics from other physiological changes associated with pregnancy and parturition (229–231), BAC of lactating women who were exclusively breastfeeding (Breastfeeding Group) were compared to a group of women whose babies were the same age but whose babies were exclusively formula fed (i.e., similar in parity but controls for recency of parturition in the absence of lactation), and a group of nulliparous women (i.e., controls for parity in the absence of lactation)

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Or, during early pregnancy, if there are concerns about fetal risks associated with peak blood levels following each once-daily dose of a psychotropic drug, twice- or thrice-daily dosing may be suggested