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Orally dosed GSH is rapidly degraded in the gut, and intravenously administered GSH is rapidly oxidized to GSSG in the blood with a half-life of 2–3 min [28,29,188,189]
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With saline medication initiated at 15 min ligation-time, controls at 1 min thereafter showed scant karyopyknosis in cerebral cortex, with increasing number of karyopyknotic neurons at 5 min thereafter
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