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Frontiers | Functional, Structural and Biochemical Features of Plant Serinyl-Glutathione Transferases
Overexpression of MRP4 in HepG2 cells is associated with a marked increase in GSH efflux (Lai and Tan, 2002), and MDCKII cells transfected with MRP5 exhibit higher GSH transport across the basolateral membrane with a concurrent decrease in intracellular GSH levels (Wijnholds et al., 2000)
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