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(1996) Effects of LY231617 and angiotensin IV on ischemia-induced deficits in circular water maze and passive avoidance performance in rats
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More recent studies on quinazoline-2,4-diones confirm that an appropriate combination of electron-withdrawing substituents and basic side chains can further enhance selectivity toward PARP-1 while maintaining a favorable pharmacokinetic profile and in vitro antitumor activity [175,176]
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