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The expression of circ-BGN is significantly increased in trastuzumab-resistant breast cancer cells and tissues compared to parental cells, and its increase is associated with poor overall survival (Wang et al., 2022a)
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Honokiol also inhibited caspase-1 activation, and apoptosis speck-like protein oligomerization, suggesting dual inhibition of NLRP3 inflammasome priming and activation processes through the modulation of the SLC3A2/L-leucine/mTORC1/NLRP3 pathways [490]
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