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Table 4: Key Safety Considerations On the cancer-risk question specifically — one of the most searched safety concerns — an FDA compounding hearing summary described the underlying mechanism directly: BPC-157 promotes angiogenesis through pathways including VEGFR2, and while no study has definitively shown BPC-157 causes cancer in humans, and no vascular tumors have been observed in animal models with prolonged use, the concern remains mechanistic and preclinical rather than resolved

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