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This controlled mitochondrial handling of Ca 2+ supports metabolic output and enables soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) and their proteins (syntaxin-2/11, SNAP-23, VAMP-7/8) mediated graded α-granule exocytosis necessary for platelet plug stabilization without producing excess thrombus (Pokrovskaya et al., 2018)
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