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PRDX-2 is also involved in the hormetic response leading to lifespan extension, where worms treated with metformin, the antihyperglycemic drug used in the treatment of type II diabetes, led to an increase in endogenous levels of H 2 O 2 [180]

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Biological evaluation showed that those structures with C-22 and C-24 side chains, 24-methyl and 24-ethylsterol fractions, increased cytotoxicity, specifically in hormone-dependent cell lines of breast and cervical cancer, although the absence of carbohydrates generates a decrease in the potency of the activity, although a latent cytotoxic effect is present