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Damaged dopaminergic neurons release matrix metalloproteinase 3, α-synuclein, and neuromelanin that superactivated microglia, inducing reactive microgliosis, enhancing of the neurotoxicity-related mediators, such ROS (Figure 3)
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these findings have demonstrated the properties of curcumin mediated by inhibition of free radicals in the liver that are impaired by alcohol consumption (23, 32)
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