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Oxidative Medicine and Novel Pharmacological Treatment Approaches in Liver Disease | Springer Nature Link
To mitigate off-target and side effects, targeted antibodies can be paired with engineered cytokine mutants that exhibit reduced receptor affinity, thereby minimizing undesired interactions between cytokines and nontarget cells
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[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Peeters P.J., Bazelier M.T., Leufkens H.G., de Vries F., De Bruin M.L
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