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Across the usual run of cell-counting, MTT, and BrdU assays, fibroblast proliferation tends to rise by something like 15% to 40% over untreated cells
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In hypoxic tumor microenvironments, hypoxia inducible factor 1 subunit alpha (HIF1A, also known as HIF1α) represses DLAT expression and confers resistance to cuproptosis 176 , supporting the existence of a HIF1A-DLAT-GSH regulatory axis
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